Based on the 2005 cinematic adaptation of C.S. Lewis' classic fantasy novel, this video game version of The Lion, the Witch, and the Wardrobe features the four Pevensie children as playable characters, each with a different specialty. Many of the game's challenges require two or more of the children to combine their strengths and work together. Only by using their talents in harmony will they be able to solve the game's action-oriented puzzles, and defeat the minotaur, cyclopes, werewolves, and other mythical monsters that stand in their way.

Peter, the oldest Pevensie child, wields a sword in the land of Narnia, and is the strongest melee fighter. The elder of his sisters, Susan, specializes in ranged attacks with her bow and arrows. The headstrong Edmund is best at making use of the environment, as he is a good climber and can use found objects as tools or weapons. The youngest sibling, Lucy Pevensie, can act as a healer when her brothers and sister are wounded. In certain situations, two of the children can team up to perform special attack moves.

During the war, while living in the safety of a large old country house, the four Londoner Pevensie children discover a magical wardrobe that serves as a portal to another world. This world of Narnia is caught in a monumental struggle, between the cruel White Witch who wishes to keep the lands frozen in a never-ending winter, and the noble lion king Aslan, who wishes to free his people from the witch's evil domination. The game's environments are based on scenes from the movie, and characters are voiced by the actors who portray them in the film.